Science

Polaritons in Periodic and Quasiperiodic Structures

In recent years there have been exciting developments in techniques for producing multilayered structures of different materials, often with thicknesses as small as only a few atomic layers. These artificial structures, known as superlattices, can either be grown with the layers stacked in an alternating fashion (the periodic case) or according to some other well-defined mathematical rule (the quasiperiodic case). This book describes research on the excitations (or wave-like behavior) of these materials, with emphasis on how the material properties are coupled to photons (the quanta of the light or the electromagnetic radiation) to produce mixed waves called polaritons. Clear and comprehensive account of polaritons in multilayered structures Covers both periodic and quasiperiodic superlattices Careful attention to theoretical developments and tools Invaluable guide for researchers in this field Shows developments from the basics to advanced topics

Polaritons in Periodic and Quasiperiodic Structures

Modern Aspects of Rare Earths and their Complexes

In order to use rare earths successfully in various applications, a good understanding of the chemistry of these elements is of paramount importance. Nearly three to four decades have passed since titles such as The Rare Earths edited by F.H. Spedding and A.H. Daane, The chemistry of the Rare Earth Elements by N.E. Topp and Complexes of the Rare Earths by S.P. Sinha were published. There have been many international conferences and symposia on rare earths, as well as the series of volumes entitled Handbook of Physics and Chemistry of Rare Earths edited by K.A. Gschneidner and L. Eyring. Thus, there is a need for a new title covering modern aspects of rare earth complexes along with the applications. The present title consists of twelve chapters. 1. Introduction 2. General aspects 3. Stability of complexes 4. Lanthanide complexes 5. Structural chemistry of lanthanide compounds 6. Organometallic complexes 7. Kinetics and mechanisms of rare earths complexation 8. Spectroscopy of lanthanide complexes 9. Photoelectron spectroscopy of rare earths 10. Lanthanide NMR shift reagents 11. Environmental ecological biological aspects 12. Applications The authors studied in schools headed by pioneers in rare earth chemistry, have a combined experience of one hundred and fifty years in inorganic chemistry, rare earth complex chemistry, nuclear and radiochemistry of rare earths and supramolecular chemistry. The present monograph is a product of this rich experience.

Modern Aspects of Rare Earths and their Complexes

Practical Guidelines in Antiviral Therapy

This text was developed with the practicing physician in mind, however, it will be of considerable interest to the virologist, pharmacologist, chemist and all scientists interested in antiviral agents. Progress in the field of antiviral development is now moving rapidly and there is hope that one day there will be successful treatment modalities for most viral diseases. This work contains contributions from experts around the world, capturing worldwide practices. An online version providing the current status of antiviral research is planned for the near future.

Practical Guidelines in Antiviral Therapy

Channelopathies

This book describes human hereditary ion channel diseases of voltage- and ligand-gated ion channels covering the diverse fields of medicine myology, neurology, cardiology, and nephrology requiring a wide and interdisciplinary readership. Interesting parallels in pathogenetic mechanisms of disease are especially emphasized to interest even highly specialized readers in entities outside of their fields. Each author has written an objective overview of his or her particular subject in a way that should allow the reader within a short period of time to obtain a comprehensive picture of the present state of art.

Channelopathies

Sexually Transmitted Diseases

There are 12 million new cases of sexually transmitted diseases every year. This growing world-wide problem has captured the concern of medical professionals, behavioural scientists, and public health officials. Sexually Transmitted Diseases: Vaccines, Prevention and Control provides a comprehensive assessment of the global epidemiology of sexually transmitted diseases plus current data on various strategies for controlling the epidemic, with particular focus on vaccines. The editors and authors represent the leading authorities in the field and provide international and multi-disciplinary expertise. This book is essential reading for all researchers and clinicians working in infectious diseases, virology, microbiology, immunology and vaccine development. This work will also be of key interest to medical students, physicians and workers in pharmaceutical and biotechnology companies and public and world health organisations. Key Features * Comprehensive coverage of epidemiology, physiology and immunology * General preventive strategies such as behavioural modification, barrier methods and topical microbicides * Individual chapters on Herpes Simplex Virus, Papillomavirus, Hepatitis B, HIV, Syphilis, Gonorrhoea, Cytomegalovirus and Chlamydia * Pathogenesis, microbiology and clinical manifestations of each STD * Current advances in vaccine development * Foreword by Julius Schachter, President of the American STD Association

Sexually Transmitted Diseases

The Genetics of Cancer

Written by internationally recognized experts, The Genetics of Cancer provides up-to-date information and insight into the genetic basis of cancer and the mechanisms involved in cancer invasion and its secondary spread. This volume presents the deregulation of the cell cycle in tumor development and integrates the function of tumor suppressor genes, oncogenes, and metastasis-associated genes in the pathogenesis and progression of cancer. The Genetics of Cancer will be useful to all graduate students, clinicians, and researchers working in the fields of cancer biology, genetics, and molecular biology. Key Features The contents include: * Clonal evolution of the metastasis phenotype * Cell Cycle regulation * Apoptosis in tumour growth and metastasis * Angiogenesis in cancer * Cell surface glycoproteins and their receptors * Proteinases and their inhibitors in cancer invasion * Oncogenes and cancer metastasis * Developmental genes * Tumour suppressor genes * Metastasis suppressor genes * Dominant metastasis-associated genes

The Genetics of Cancer

The Neurospora Compendium

The fungi have been major players in the molecular revolution that has transformed biology. Because they can be manipulated as microorganisms, yeast and Neurospora provide information that is difficult to acquire with plants and animals, and experimental findings with fungi often throw light on corresponding processes in plants and animals. The filamentous fungus Neurospora crassa has become a valuable model organism because of its favorable features for genetic analysis and because of the vast store of information that has been acquired during 75 years of research. This compendium provides researchers and students with a concise account of current knowledge about the genes and genome of Neurospora, setting the stage for research that will follow completion of the genome sequence. This book, which is fully documented and abundantly illustrated, will be an indispensable tool in any laboratory that uses fungi for research in molecular genetics, classical genetics, developmental genetics, or cell biology. Key Features * Molecular, genetic, and phenotypic information for over 1000 nuclear genes * Genetic maps. * Linkage group assignments for 1000 loci * 2300 references, 68 figures * Guide to electronic and other sources of information * Summary information on the mitochondrial genome * cDNAs identified from different stages of life * Classical, cytogenetic, and molecular data, anticipating completion of the genome sequence

The Neurospora Compendium

Hormones

The newly revised and updated Hormones, Second Edition provides a comprehensive treatment of human hormones, viewed in light of modern theories of hormone action and in the context of current understanding of subcellular and cellular architecture and classical organ physiology. Each chapter presents a physiological description of the hormone system under consideration, followed by a listing of the mode-of-action of the hormone. This book includes significant advances in the molecular biology of receptors, hormones, and studies of hormone action that have transpired over the past five years. The text updates the material on enzymes related to steroid metabolism and new hormone systems, as well as providing a new chapter on hormones and cancer. Key Features * Completely updates the material, covering new discoveries and significant advances since the First Edition was published in 1987 * Contains new information regarding steroid hormones, the role of hormones in cancer, and a comprehensive introductory chapter * Presents an overview of virtually all important hormones * Provides detailed physiological, cellular, and molecular descriptions of classical human endocrine systems * Streamlines the presentation of the First Edition, making the book easier to use and read

Hormones

Macrolide Antibiotics

Macrolide Antibiotics: Chemistry, Biochemistry, and Practice, Second Edition explores the discovery of new macrolide antibiotics, their function, and their clinical use in diseases such as cancer, AIDS, cystic fibrosis and pneumonia. This book discusses the creation of synthetic macrolides and the mechanisms of antibiotic activity. The uses for antimicrobial macrolides in clinical practice are also covered. This book is designed to appeal to both the basic and applied research communities interested in microbiology, bacteriology, and antibiotic/antifungal research and treament.

Macrolide Antibiotics

The Many Faces of RNA

The Many Faces of RNA is the subject for the eighth SmithKline Beecham Pharmaceuticals Research Symposia. It highlights a rapidly developing area of scientific investigation. The style and format are deliberately designed to promote in-depth presentations and discussions and to facilitate the forging of collaborations between academic and industrial partners. This symposium focuses on several of the many fundamental, advancing strategies for exploring RNA and its functions. It emphasizes the interplay between biology, chemistry, genomics, and molecular biology which is leading to exciting new insights and avenues of investigation. The book explores RNA as a therapeutic target, RNA as a tool, RNA and its interactions, along with chemical, computational, and structural investigations.

The Many Faces of RNA

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